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Motoyasu Kusano Selected Research

Rabeprazole (Aciphex)

7/2018Efficacy and safety of twice-daily rabeprazole maintenance therapy for patients with reflux esophagitis refractory to standard once-daily proton pump inhibitor: the Japan-based EXTEND study.
3/2018Therapy of gastroesophageal reflux disease and functional dyspepsia overlaps with symptoms after usual-dose proton pump inhibitor: Acotiamide plus usual-dose proton pump inhibitor versus double-dose proton pump inhibitor.
1/2018Efficacy and Safety Profile of Z-215 (Azeloprazole Sodium), a Proton Pump Inhibitor, Compared with Rabeprazole Sodium in Patients with Reflux Esophagitis: A Phase II, Multicenter, Randomized, Double-Blind, Comparative Study.
1/2017Therapeutic Response to Twice-daily Rabeprazole on Health-related Quality of Life and Symptoms in Patients with Refractory Reflux Esophagitis: A Multicenter Observational Study.
7/2014Clinical characteristics of elderly patients with proton pump inhibitor-refractory non-erosive reflux disease from the G-PRIDE study who responded to rikkunshito.
1/2013Sleep disturbances and refractory gastroesophageal reflux disease symptoms in patients receiving once-daily proton pump inhibitors and efficacy of twice-daily rabeprazole treatment.
11/2012Clinical symptoms of FSSG in gastroesophageal reflux disease are critical for PPI treatment: Japanese multi-centers with 185 patients.
5/2012Symptoms and quality of life in underweight gastroesophageal reflux disease patients and therapeutic responses to proton pump inhibitors.
3/2012Rikkunshito improves symptoms in PPI-refractory GERD patients: a prospective, randomized, multicenter trial in Japan.
11/2011Investigation of pretreatment prediction of proton pump inhibitor (PPI)-resistant patients with gastroesophageal reflux disease and the dose escalation challenge of PPIs-TORNADO study: a multicenter prospective study by the Acid-Related Symptom Research Group in Japan.
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Motoyasu Kusano Research Topics

Disease

21Gastroesophageal Reflux (GERD)
01/2020 - 08/2004
10Peptic Esophagitis (Reflux Esophagitis)
07/2018 - 04/2010
10Dyspepsia (Indigestion)
03/2018 - 07/2007
8Non-Erosive Reflux Disease
08/2016 - 12/2008
5Neoplasms (Cancer)
01/2018 - 01/2007
4Infections
08/2018 - 01/2017
4Heartburn (Pyrosis)
03/2018 - 12/2010
4Chronic Hepatitis C
02/2018 - 12/2015
3Esophagitis
01/2020 - 01/2016
3Inflammation (Inflammations)
01/2014 - 01/2006
2Chronic Kidney Failure (Chronic Renal Failure)
01/2017 - 03/2016
2Insulin Resistance
03/2016 - 01/2015
2Non-alcoholic Fatty Liver Disease
03/2016 - 01/2015
2Hemorrhage
02/2016 - 02/2015
2Stomach Ulcer (Gastric Ulcer)
12/2015 - 01/2003
2Asthma (Bronchial Asthma)
01/2014 - 07/2006
2Stomach Neoplasms (Stomach Cancer)
08/2011 - 01/2003
1Fibrosis (Cirrhosis)
12/2018
1Cryoglobulinemia
08/2018
1Ascites
08/2018
1Proteinuria
08/2018
1Hypoalbuminemia
08/2018
1Edema (Dropsy)
08/2018
1Hyperuricemia
02/2018
1Colonic Neoplasms (Colon Cancer)
01/2018
1Connective Tissue Diseases (Connective Tissue Disease)
04/2017
1Hematologic Diseases (Blood Diseases)
04/2017
1Pruritus (Itching)
01/2017
1Liver Failure
01/2017
1Jaundice (Icterus)
01/2017
1Esophageal and Gastric Varices (Esophageal Varices)
01/2017
1Hepatic Encephalopathy
01/2017
1Multiple Sclerosis
01/2017
1Heart Failure
03/2016
1Morbid Obesity
03/2016
1Body Weight (Weight, Body)
03/2016
1Respiratory Sounds (Crackle)
02/2016
1Dyspnea (Shortness of Breath)
02/2016
1Isaacs Syndrome (Neuromyotonia)
02/2016
1Tics (Tic)
01/2016
1Hepatocellular Carcinoma (Hepatoma)
01/2016

Drug/Important Bio-Agent (IBA)

22Proton Pump InhibitorsIBA
01/2020 - 09/2004
12Rabeprazole (Aciphex)FDA Link
07/2018 - 12/2008
9AcidsIBA
01/2020 - 07/2006
4liu-jun-zi-tangIBA
08/2016 - 03/2012
3Antiviral Agents (Antivirals)IBA
08/2018 - 03/2016
2AutoantibodiesIBA
11/2019 - 01/2006
2daclatasvirIBA
08/2018 - 12/2015
2asunaprevirIBA
08/2018 - 12/2015
2Z 338IBA
03/2018 - 12/2014
2UreaseIBA
01/2018 - 01/2017
2InterferonsIBA
01/2017 - 12/2015
2Aspartate Aminotransferases (Aspartate Transaminase)IBA
03/2016 - 01/2015
2Alanine Transaminase (SGPT)IBA
03/2016 - 01/2015
2AntibodiesIBA
02/2016 - 01/2015
2Famotidine (Pepcid)FDA LinkGeneric
12/2010 - 04/2010
2lafutidineIBA
12/2010 - 04/2010
1GastrinsIBA
01/2020
11- (5- (2- fluorophenyl)- 1- (pyridin- 3- ylsulfonyl)- 1H- pyrrol- 3- yl)- N- methylmethanamineIBA
01/2020
1PotassiumIBA
01/2020
1Dihydrotachysterol (AT 10)IBA
07/2018
1SofosbuvirIBA
02/2018
1Uric Acid (Urate)IBA
02/2018
1Ribavirin (Virazole)FDA LinkGeneric
02/2018
1Carcinoembryonic AntigenIBA
01/2018
12- (4- (2,2- dimethyl- 1,3- dioxan- 5- yl)methoxy- 3,5- dimethylpyridin- 2- yl)methylsulfinyl- 1H- benzimidazoleIBA
01/2018
1Sodium-Glucose Transport ProteinsIBA
01/2018
1Cetuximab (Erbitux)FDA Link
01/2018
1paritaprevirIBA
01/2017
1Ritonavir (Norvir)FDA Link
01/2017
1Valsartan (Vals)FDA Link
01/2017
1ombitasvirIBA
01/2017
1Histamine (Histamine Dihydrochloride)FDA Link
08/2016
1C-PeptideIBA
03/2016
1gamma-Glutamyltransferase (gamma-Glutamyl Transpeptidase)IBA
03/2016
1Glucose (Dextrose)FDA LinkGeneric
03/2016
1Hemoglobins (Hemoglobin)IBA
03/2016
1Insulin (Novolin)FDA Link
03/2016
1Flunitrazepam (Rohypnol)IBA
02/2016
1Voltage-Gated Potassium Channels (Voltage-Gated Potassium Channel)IBA
02/2016
1Flumazenil (Romazicon)FDA LinkGeneric
02/2016
1Hydroxyzine (Vistaril)FDA LinkGeneric
02/2016
1Prothrombin (Factor II)IBA
01/2016
1Cisplatin (Platino)FDA LinkGeneric
01/2016
1PowdersIBA
01/2016

Therapy/Procedure

21Therapeutics
08/2018 - 07/2007
3Drug Therapy (Chemotherapy)
04/2017 - 01/2007
2Fundoplication
12/2018 - 11/2004
2Aftercare (After-Treatment)
03/2012 - 07/2007
2Gastrectomy
01/2012 - 08/2011
1Hemodiafiltration
01/2017
1Critical Care (Surgical Intensive Care)
01/2017
1Sclerotherapy
01/2017
1Plasma Exchange
01/2017
1Contraindications
03/2016
1Percutaneous Coronary Intervention
03/2016
1Bariatric Surgery
03/2016
1Intravenous Injections
02/2016
1Conscious Sedation
02/2016
1Ligation
02/2016